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Chiropractic Adjustments and Pain Modulation: Central Mechanisms Explained

Chiropractic adjustments modulate cortical and subcortical regions involved in pain processing. Changes in SEPs reflect decreased sensory hyperexcitability and improved integration. Supports a central, neurophysiological mechanism for pain relief rather than purely structural change. Reinforces the modern understanding of chiropractic care as influencing brain-body communication and perception, not just joints and muscles.

Original Study Title:

Cervical Spine Manipulation Alters Sensorimotor Integration: A Somatosensory Evoked Potential Study

Authors:

Heidi Haavik-Taylor; Bernadette Murphy

Journal:

Clinical Neurophysiology

Publication Year:

2007
Haavik-Taylor, H., & Murphy, B. (2007). Cervical Spine Manipulation Alters Sensorimotor Integration: A Somatosensory Evoked Potential Study. Clinical Neurophysiology, 118(2), 391-402. https://doi.org/10.1016/j.clinph.2006.09.027

Understanding pain modulation

Pain is not simply a signal from injured tissue — it’s a complex experience shaped by how the brain interprets sensory input. The spinal cord and brain constantly filter and adjust these signals through a system known as central pain modulation. Research led by Dr Heidi Haavik and colleagues has shown that chiropractic spinal adjustments can influence this process, changing how the nervous system processes and perceives pain.

What the research explored

Using EEG, SEPs (somatosensory evoked potentials), and fMRI, researchers examined how spinal manipulation alters cortical and subcortical activity in regions involved in pain perception — including the somatosensory cortex, thalamus, and anterior cingulate cortex. The goal was to understand whether spinal adjustments activate descending inhibitory pathways that help regulate pain sensitivity.

Key findings

  • Chiropractic adjustments changed pain-related brain activity in regions responsible for sensory and emotional aspects of pain.
  • Post-adjustment recordings showed reduced cortical N30 SEP amplitude, indicating altered sensory integration and decreased hyperexcitability.
  • Functional imaging revealed enhanced connectivity in brain networks associated with endogenous pain inhibition.
  • Participants often reported decreased pain sensitivity, even without changes in local tissue — supporting a central rather than purely mechanical mechanism.

Clinical implications

These findings suggest that spinal adjustments may help the nervous system recalibrate its pain thresholds — not by blocking pain, but by improving how the brain interprets sensory information. This may help explain why many patients experience relief beyond the immediate area adjusted.

In practice

  • We focus on identifying and correcting dysfunctional spinal segments contributing to altered sensory feedback.
  • Care is combined with movement, breathing, and postural strategies that reinforce healthy neural patterns.
  • By improving sensorimotor integration, chiropractic adjustments can support the body’s natural pain-regulation systems.

Read the study: Cervical Spine Manipulation Alters Sensorimotor Integration: A Somatosensory Evoked Potential Study


This research summary is for educational purposes only. Chiropractic adjustments do not “treat” pain directly, but may influence how the nervous system perceives and manages it.

The information on this page summarises independent, peer-reviewed research conducted by external scientists. It is provided for educational purposes only and does not imply that chiropractic care treats or cures any medical condition. Chiropractic services at this clinic are provided within the scope of practice defined by the Chiropractic Board of New Zealand.