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Sensory Processing After Spinal Adjustments: The N30 SEP Story

A single session of HVLA cervical spine manipulation resulted in a ~20% reduction in N30 SEP amplitude in subjects with recurrent neck stiffness/pain. Changes lasted around 20 minutes post-adjustment. Control (passive head movement) showed no change, pointing to the specificity of the manipulation effect. Suggests dysfunctional cervical joints may influence early cortical processing of sensory input and that adjustment can produce rapid neurophysiological changes.

Original Study Title:

Cervical spine manipulation alters sensorimotor integration: a somatosensory evoked potential study.

Authors:

Heidi Haavik-Taylor; Bernadette Murphy.

Journal:

Clinical Neurophysiology.

Publication Year:

2007
Haavik-Taylor, H., & Murphy, B. (2007). Cervical spine manipulation alters sensorimotor integration: a somatosensory evoked potential study. Clinical Neurophysiology, 118(2), 391-402. https://doi.org/10.1016/j.clinph.2006.09.027

What this study examined

The study investigated how a single session of high-velocity low-amplitude (HVLA) cervical spine manipulation affects early cortical somatosensory processing — specifically the N30 somatosensory evoked potential (SEP) — in adults with recurrent neck stiffness or sub-clinical neck pain. Participants underwent median nerve stimulation and SEP recordings before and up to 30 minutes after the manipulation or a passive head-movement control.

Why the N30 SEP matters

The N30 SEP peak represents early cortical processing of somatosensory input, particularly reflecting sensorimotor integration in brain areas such as the pre-frontal and premotor cortices. Changes in N30 amplitude suggest alterations in how the brain integrates sensory information from the body and may affect movement control, coordination and pain perception.

Key findings

  • The amplitude of the N30 SEP decreased significantly following one session of cervical spine manipulation (≈20% reduction) compared to pre-manipulation baseline. :contentReference[oaicite:0]{index=0}
  • The reduction in N30 amplitude lasted on average 20 minutes post-manipulation. :contentReference[oaicite:1]{index=1}
  • No significant changes were observed in the control (passive head movement) condition, suggesting the changes were specific to manipulation. :contentReference[oaicite:2]{index=2}

What this means for practice

These findings support the hypothesis that spinal joint dysfunction can influence how the brain processes sensory input from the body, and that a spinal adjustment may produce immediate cortical changes. In practical terms, this suggests that when we restore spinal joint motion and alignment, we may not only improve local joint function but also enhance sensorimotor integration — potentially improving movement quality, coordination and reducing compensatory tension.

Applying it in our care approach

  • Assess for segmental dysfunction in the cervical spine and address it with precise HVLA adjustments as appropriate.
  • Support the adjustment with movement-based exercises and sensorimotor drills (balance, coordination) to reinforce central changes.
  • Monitor functional outcomes (e.g., posture, balance, head/neck motion, movement control) rather than solely pain reduction.

Read the study: Cervical spine manipulation alters sensorimotor integration: a somatosensory evoked potential study.


Note: This summary is informational only and not a claim of treatment for any condition. Clinical outcomes vary. Please discuss suitability of this care approach with your chiropractor.

The information on this page summarises independent, peer-reviewed research conducted by external scientists. It is provided for educational purposes only and does not imply that chiropractic care treats or cures any medical condition. Chiropractic services at this clinic are provided within the scope of practice defined by the Chiropractic Board of New Zealand.